Showing posts with label Drugs. Show all posts
Showing posts with label Drugs. Show all posts

Thursday, September 26, 2013

How big of a role does environment play in addiction?


What role does environment and distress play in addiction? Below is an interesting scientific study whose controversial findings were published in a respectable journal named Psychopharmacology back in 1978 which lead to the university terminating the project. It would be interesting to see what role stressful environments impact other forms of addiction. Also how communities could be improved to lower suffering and self destructive behavior. If scientific freedom actually existed and projects were funded for the good of humanity in lieu of profits and mechanisms of control we would all live in a much happier world. Something defiantly worth exploring.. 

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It's not the morphine, it's the size of the cage: Rat Park experiment upturns conventional wisdom about addiction

We all learned this in DARE class. About the rats in a cage who can self-administer morphine who get addicted to the stuff, and then just hit that lever until they die. A seemingly keystone argument in the war against drugs. Professor Avram Goldstein, the creator of that study, has said: "A rat addicted to heroin is not rebelling against society, is not a victim of socioeconomic circumstances, is not a product of a dysfunctional family, and is not a criminal. The rat's behavior is simply controlled by the action of heroin (actually morphine, to which heroin is converted in the body) on its brain." So, it's the drug, and its addictive control. Surely we must eradicate drugs as a result! 

But there's another model out there by researcher Bruce Alexander of Simon Fraser University called Rat Park. From that wikipedia page: 

Alexander's hypothesis was that drugs do not cause addiction, and that the apparent addiction to opiate drugs commonly observed in laboratory rats exposed to it is attributable to their living conditions, and not to any addictive property of the drug itself. He told the Canadian Senate in 2001 that prior experiments in which laboratory rats were kept isolated in cramped metal cages, tethered to a self-injection apparatus, show only that "severely distressed animals, like severely distressed people, will relieve their distress pharmacologically if they can."

To test his hypothesis, Alexander built Rat Park, an 8.8 m2 (95 sq ft) housing colony, 200 times the square footage of a standard laboratory cage. There were 16–20 rats of both sexes in residence, an abundance of food, balls and wheels for play, and enough space for mating and raising litters. The results of the experiment appeared to support his hypothesis. Rats who had been forced to consume morphine hydrochloride for 57 consecutive days were brought to Rat Park and given a choice between plain tap water and water laced with morphine. For the most part, they chose the plain water. "Nothing that we tried," Alexander wrote, "... produced anything that looked like addiction in rats that were housed in a reasonably normal environment." Control groups of rats isolated in small cages consumed much more morphine in this and several subsequent experiments.

And so rats that are born into extreme conditions in small cages are clearly more likely to self-medicate. Tom Stafford of the BBC writes: 

The results are catastrophic for the simplistic idea that one use of a drug inevitably hooks the user by rewiring their brain. When Alexander's rats were given something better to do than sit in a bare cage they turned their noses up at morphine because they preferred playing with their friends and exploring their surroundings to getting high.

Further support for his emphasis on living conditions came from another set of tests his team carried out in which rats brought up in ordinary cages were forced to consume morphine for 57 days in a row. If anything should create the conditions for chemical rewiring of their brains, this should be it. But once these rats were moved to Rat Park they chose water over morphine when given the choice, although they did exhibit some minor withdrawal symptoms.

You can read more about Rat Park in the original scientific report. A good summary is in this comic by Stuart McMillen.

So, if Rat Park is to be believed, drug addiction is a situation that arises from poor socioeconomic conditions. From literally being a rat in a cage. If you're a rat in a park, you'd rather hang out with your friends and explore the world around you. 

Perhaps it's time the war on drugs becomes a war on the existence of poverty? (edit: Poverty of our relationships to family, community, and nation too, not merely monetary. As commenters have pointed out, there are plenty of people who have plenty of money who may well be the most poverty-ridden in other respects.)

It's not about the drugs. It's about the social environment in which we live.

Source: Garry Tan

Tuesday, February 7, 2012

A Conversation On LSD

A rare home movie of a conversation between early LSD pioneers Timothy Leary, Oscar Jangier, Al Hubbard, Sidney Cohen, Myron Stolaroff and Humphry Osmond & others. A must see for psychedelic historians. I believe this was filmed at Tim’s home circa 1972.Thank you Timothy Leary Archive!



Download:
512Kb MP4 <-Right Click, Save Target as
14GB Digital Video Format Link

Monday, January 23, 2012

The Marketing of Madness: The Truth About Psychotropic Drugs

The Marketing of Madness is the definitive documentary on the psychiatric drugging industry. Here is the real story of the high income partnership between psychiatry and drug companies that has created an $80 billion psychotropic drug profit centre.

But appearances are deceiving. How valid are psychiatrists’ diagnoses – and how safe are their drugs? Digging deep beneath the corporate veneer, this three-part documentary exposes the truth behind the slick marketing schemes and scientific deceit that conceal dangerous and often deadly sales campaigns.

In this film you’ll discover that… Many of the drugs side effects may actually make your ‘mental illness’ worse. Psychiatric drugs can induce aggression or depression. Some psychotropic drugs prescribed to children are more addictive than cocaine. Psychiatric diagnoses appears to be based on dubious science. Of the 297 mental disorders contained with the Diagnostic and Statistical Manual of Mental Disorders, none can be objectively measured by pathological tests.

Mental illness symptoms within this manual are arbitrarily assigned by a subjective voting system in a psychiatric panel. It is estimated that 100 million people globally use psychotropic drugs.

The Marketing of Madness exposes the real insanity in our psychiatric ‘health care’ system: profit-driven drug marketing at the expense of human rights.

This film plunges into an industry corrupted by corporate greed and delivers a shocking warning from courageous experts who value public health over dollar.

Wednesday, October 26, 2011

Manifesting The Mind : Documentary On Psychedelics & Shamanism

Manifesting the Mind features various aspects of shamanism with a broad look at psychedelics in general. Why are psychedelics so brutally suppressed in our culture? What exactly are some of the psychedelic plants and chemicals and how can they benefit us? With philosophy and insight from Robert Bussinger, Mike Crowley, Timothy Freke, Peter Gandy, Alex Grey, Clark Heinrich, Nick Herbert, John Major Jenkins, Dennis McKenna, Terence McKenna, Daniel Pinchbeck, Dr. Rick Strassman & others.

Chapter 1 – Start
An introduction to shamanism and shamanic medicines.

Chapter 2 – Manifesting God?
A discussion regarding the word “Entheogen” verses other words such as “Psychedelic” to describe shamanic medicines and psychoactive substances.

Chapter 3 – Psychedelic Fanatic
What are the effects of psychedelics and are these psychedelic substances addictive?

Chapter 4 – Psychedelic Remedy
Cannabis and other shamanic medicines used medicinally

Chapter 5 – Drugs and Culture
From coffee to cocaine… What constitutes a “bad drug”?

Chapter 6 – War on Consciousness
Is the war on drugs a war against certain states of consciousness?

Chapter 7 – Ibogaine
Can a shamanic medicine cure heroin, meth, alcohol and other addictions?

Chapter 8 – DMT
DMT, the most hallucinogenic substance known to exist, is found naturally in the human body and in nearly every other living thing.

Chapter 9 – Ayahuasca
What are the components and the effects of Ayahuasca? How is it different than other forms of DMT?

Chapter 10 – Reality Thermostat
Where do the boundaries between our selves and the world exist? Are hallucinations “real”? What is ego-death? What can be learned from a psychedelic experience?

Chapter 11 – Controlling the Masses
We are groomed to be consumers - this is encouraged via propaganda - as long as we consume those things that are sanctioned by the corporate hegemony.

Chapter 12 – Manifesting Change
Turn on, Tune in, and Drop out. Psychedelics as a catalyst for change.

Chapter 13 – Amanita muscaria
This archetypal mushroom has been used in religious art and modern iconography. How does it compare to other psychedelic substances?

Chapter 16 – Religious Roots
Psychedelic substances can often be found in early religious traditions.

Chapter 17 – Flesh of the Gods
The religious/spiritual experience. What is the origin of the sacred meal? Did the original “communion” induce a psychedelic experience? The replacement of the shamanic sacrament with a placebo.

Chapter 18 – The Heart of the Mysteries
Has the direct access to the mysteries been cut off from our modern culture?

Chapter 19 – Soma
What was the original Soma and Amrita?

Chapter 20 – Credits and Biographies

Buy the DVD

Sunday, July 3, 2011

Aldous Huxley: Mp3 Interview

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An Interview with Aldous Huxley
"Capital A, Capital R" Circa 1959
Transcribed by Plutonic / From
EROWID
Originally published by British Library Sound Archive

DOWNLOAD MP3 BELOW (5:38 Min - 8MB)
Aldous Huxley Interview Right Click, Save Target As.

Q: How often have you taken mescaline yourself?

A: I've taken mescaline twice, and lysergic acid about 5 times I suppose. I would like to take it about once a year I think. When one [oh] doesn't ... most people that I know who take it have no desire to sort of fool with it, or take it constantly, I mean the thing take it too seriously to, to behave in this way towards it, you wouldn't want to wallow in it. I mean you needed a good enough time to digest this I think, I mean I don't know, most people I know that eat it don't have any special desires to go on taking it, I mean they would like to take it every six months or every year, something of that kind. But I still have to meet one who wants to take it constantly.

Q: But isn't it a condition that one would want to be in all the time?

A: You couldn't be in it all the time cause it's so to say beyond the level of biological efficiency. The world becomes so extraordinary and so absorbing that you couldn't cross the street without considerable risk of being run over. You wouldn't want to do anything else because just experiencing this thing is so extraordinary.

Q: Is the effect the same on everyone?

A: Statistically about 70 percent, 75 percent probably get a good and positive happy result from it, and a certain percentage get no results, a certain percentage get very unpleasant and ill-like results out of it, get very frightened. Mine were always positive, I didn't have what some people have which is a great elaborate visions with the eyes closed, some people have the most elaborate and circumstantial visionary experiences with the eyes closed. I merely see sort of living geometries but never any of these great landscapes and figures and architectures which some people see.

Q: Do you sit, or do you move about?

A: I've spent a lot of time sitting quietly looking at things, and getting these sort of strange metaphysical insights into the world.

Q: Is it a habit forming drug?

A: In most occasions it has no more hangover then two cocktails, some people feel actually much better the next day. It's being used to some extent in therapy, there's a man here called Sandison that uses it a lot, there are several people in America, in Canada several groups have had very very good results with alcoholism using LSD.

There's a new drug now, psilocybin, which is derived from the Mexican mushroom which has the same effect but doesn't last quite so long. And that it is being used in France therapeutically with some success. Mescaline you take a capsule of 400 milligrams and the lysergic acid you take this incredibly small dose of 100 gamma, which is 100 millionths of a gram, a ten thousandth of a gram, a 10th of a milligram which is a homeopathic dose, it's perfectly extraordinary it should have any effect and in fact it has an effect long after all traces of it have gone out of the body, it has an effect by triggering some... nobody knows exactly what, probably inhibits one of the 27 enzymes which control the functioning of the brain, either inhibits one or stimulates one and I don't think anyone quite knows what it does.

The intensity of the experience is entirely unlike any ordinary experience, but on the other hand it quite obviously resembles spontaneous experiences certain artists and religious people have unquestionably had. It's an immense intensification of the world, a transfiguration of the external world into incredible beauty and significance. It's also beyond this kind of aesthetic experience, there may be other experience, a sense of solidarity with the universe, solidarity with other people, understanding of such phrases as you get in the book of Job: "Yeah, Though He Slay Me, Yet Will I Trust In Him", it becomes quite comprehensible. This thing opens the door to these experiences which can be of immense value to people if they choose to make use of them. If they don't choose to, I mean this is what the Catholics call a gratuitous grace, it doesn't guarantee salvation or it's not sufficient and it's not necessary to salvation but if it can be collaborated with and used in an intelligent way it can be an immense help to people. This sense that in spite of everything which of course is the ultimate, I suppose, the ultimate mystical conviction in spite of pain, in spite of death, in spite of horror, the universe is in some mysterious sense is all right, capital A capital R.

Wednesday, May 25, 2011

San Francisco Gathering Sets

The Gathering Sets

These MP3 files are created from WAV files, which were generated from the DATs recorded from the mixing desk at each party.

The_Gathering_1

We started recording with audio tapes from 1992 to 1996, and with DAT from 1996 onwards. We intend to create MP3 files from the content of the audio tapes and post them here over the next few months.

Tuesday, May 3, 2011

UC Berkeley : Drugs and Behavior

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University of California Berkeley
Psych 119 Drugs and Behavior
Instructor
David Presti, Ph.D.
Senior Lecturer of Neurobiology, his areas of expertise include the chemistry of the human nervous system, the effects of drugs on the brain and mind, and the scientific study of mind and consciousness.

Course Syllabus for 2010

ASUC Lecture Notes Online

Psych 119: Drugs and the Brain. A survey course exploring the basic principles of psychopharmacology. The major focus of the course is on the relationship between behavior and the physiological actions of drugs. Emphasis will be placed on effects of pharmacological agents on complex mental processes such as attention, motivation, learning, and memory.

Subscribe Subscribe to the Psych 119 podcast

Psych 119: Lecture 1


Psych 119: Lecture 2


Psych 119: Lecture 3


Psych 119: Lecture 4


Psych 119: Lecture 5


Psych 119: Lecture 6


Psych 119: Lecture 7


Psych 119: Lecture 8


Psych 119: Lecture 9


Psych 119 - Lecture 10


Psych 119: Lecture 11


Psych 119: Lecture 13


psych 119: Lecture 14


Psych 119: Lecture 15


Psych 119: Lecture 16


Psych 119: Lecture 17


Psych 119: Lecture 18


Psych119_Lecture 19


Psych 119: Lecture 20


Psych 119: Lecture 21


Psych 119: Lecture 22


Psych 119: Lecture 23


Psych 119: Lecture 25


Psych119: Lecture 27


Psych 119: Lecture 28


Psych 119: Lecture 29

David Presti

Quiz Answer Forms

New York City Marijuana Arrest Analysis 2008

"Letting Go: Smoking and non-smoking" by David Sedaris

Tips for Quitting Smoking

SAMHSA and NIDA Tobacco Use Data

SAMHSA Alcohol Use Data

Cannabis Prevalence Data

Some approximate caffeine contents


William James